Pregnancy & Prenatal Testing
Third Trimester: Fetal Fibronectin
A cervical or vaginal fluid sample is collected and analyzed for fFN, a glycoprotein found at the boundary between the amniotic sac and the lining of the uterus. High levels can be due to causes other than risk of pre-term delivery; therefore, a positive fFN result is not very predictive of preterm labor and delivery. However, a negative fFN result is highly predictive that preterm delivery will not occur within the next 7-14 days. Since there are risks associated with treating a woman for premature labor (in anticipation of a premature delivery), a negative fFN can reduce unnecessary hospitalizations and drug therapies.
Links
March of Dimes: Fetal fibronectin




