Treatments vary depending on the reason for the pituitary disorder. Medications may be used to block hormone action, supplement missing or deficient hormones, and shrink pituitary tumors (to reduce compression symptoms and sometimes prior to surgery). When a pituitary tumor is present, surgery may be done to either remove the tumor or remove most of the tissue when all of it cannot be removed. The pituitary gland is accessed through the nose (transsphenoidal surgery). The procedure is delicate and requires a surgeon that is experienced in the procedure. Targeted radiation therapy may be used in conjunction with other treatments to decrease tumor size and excess hormone production.

Patients should work with their doctor and/or an endocrinologist (a doctor that specializes in the endocrine system) to determine the best treatment(s) for them.