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Lymphoma
The following table illustrates the two most commonly used classifications plus an older classification. Because of differences in how the lymphomas are described, there is not a one-to-one comparison between the systems, and a single disease could be known by multiple names.

Comparison of Some Non-Hodgkin Lymphoma Classifications
Note: These classifications cannot always be compared

 NCI* (Working   Formulation) (Older Classification)  REAL**  WHO*** Classification

 

 B cell lineage/NHL  Mature B cell     lymphoma

Low grade lymphoma    Small lymphocytic lymphoma               
Small lymphocytic lymphoma (plasmacytoid)                            


Follicular lymphoma (small
cleaved cell, large cell, mixed cell)        

High Grade lymphoma
Diffuse lymphoma (small  cleaved, large, mixed cell) Diffuse immunoloblastic lymphoma 
Burkitt Lymphoma

Burkitt-like Lymphoma
Lymphoblastic lymphoma

 B-cell chronic lymphocytic leukemia       Lymphoplasmacytic lymphoma            
Nodal and extranodal marginal B-cell lymphoma               

Follicular Center, grades I, II, and III lymphoma
  



Mantle Cell lymphoma
  
B cell CLL / SLL   Splenic marginal zone B-cell lymphoma Extranodal marginal B cell lymphoma  



Follicular lymphoma 
                       


Mantle cell lymphoma
 

Diffuse large B-cell lymphoma
        

Burkitt’s lymphoma

T and NK Cell Neoplasms

 

T and NK Cell Neoplasms

 

 

Mature T cell lymphoma
Small lymphocyte lymphoma 

Mycosis Fungoides
      


Diffuse lymphoma (small
cleaved, large, mixed cell)  



Large cell immunoblastic lymphoma         
   

 

Adult T cell lymphoma    

Mycosis fungoides (S�zary Syndrome)
 

Anaplastic large cell 
lymphoma not otherwise characterized 

Immunoblastic T cell lymphoma

 

 

Langerhans cell histiocytosis 

Langerhans cell sarcoma
 

Interdigitating dendritic cell sarcoma/tumor
 

Follicular dendritic cell
sarcoma/tumor 

Dendritic cell sarcoma, not otherwise specified

* NCI = National Cancer Institute

** REAL = Revised European American Lymphoma

*** WHO = World Health Organization


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This article last reviewed on February 14, 2007.
 
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