Hypercoagulable Disorders

On This Site
Tests: ACT, PTT, CBC, Coagulation factors, D-dimer, Fibrinogen, Homocysteine, Lupus Anticoagulant, Proteins C & S, PT, PT 20210 and Factor V Leiden, Heparin Anti-Xa
Conditions: Bleeding disorders, Liver disease, Lupus
In the News: Genetic Tests Offer New Approach to Warfarin Dosing (2009), How long to stay on anticoagulants: Study taps D-dimer test for answers (2007)

Elsewhere On The Web
National Alliance for Thrombosis & Thrombophilia (NATT)
FDA Consumer Magazine: Avoid Deep Vein Thrombosis: Keep the Blood Flowing
American Heart Association: Thrombolysis, Thrombosis, Thrombus and Embolus
University of Illinois, Urbana/Champaign: Carle Cancer Center Hematology Resource Page, Patient Resources
The International Society on Thrombosis and Haemostasis

Article Sources

NOTE: This article is based on research that utilizes the sources cited here as well as the collective experience of the Lab Tests Online Editorial Review Board. This article is periodically reviewed by the Editorial Board and may be updated as a result of the review. Any new sources cited will be added to the list and distinguished from the original sources used.

Thomas, Clayton L., Editor (1997). Taber’s Cyclopedic Medical Dictionary. F.A. Davis Company, Philadelphia, PA [18th Edition].

Pagana, Kathleen D. & Pagana, Timothy J. (2001). Mosby’s Diagnostic and Laboratory Test Reference 5th Edition: Mosby, Inc., Saint Louis, MO.

Coagulation Test Panels. Clinical and Research Laboratories, Florida Hospital Cancer Institute [On-line information]. Available online at http://www.fhci-labs.com/researchlabs/clinicallabs/hemostasisandthrombosis/panels.htm through http://www.fhci-labs.com.

Ryan, D. (2003 January). Platelet Function Testing. Strong Health Clinical Laboratories Newsletter, Vol. 28, No. 1 [On-line newsletter]. Available online at http://www.urmc.rochester.edu/path/newsletter103.htm through http://www.urmc.rochester.edu.

Laposata, M. & Vancott, E. (2000 January). How to work up hypercoagulability. CAP In the News [On-line Coagulation Case Study]. Available online at http://www.cap.org/CAPToday/casestudy/coag5.html through http://www.cap.org.

Bleeding Disorders. The Merck Manual of Medical Information-Home Edition, Section 14. Blood Disorders, Chapter 155 [On-line information]. Available online at http://www.merck.com/mrkshared/mmanual_home/sec14/155.jsp through http://www.merck.com.

Venomous Bites and Stings. The Merck Manual of Medical Information-Home Edition, Section 24. Accidents and Injuries, Chapter 287 [On-line information]. Available online at http://www.merck.com/mrkshared/mmanual_home/sec24/287.jsp through http://www.merck.com.

Lee, D. (2000 July 24). Platelet Aggregometry. Stanford Interventional Cardiology [On-line information]. Available online at http://cvmed.stanford.edu/interventional/aggregometry.htm through http://cvmed.stanford.edu.

Cortese Hassett, A. (2002). Platelet Function Testing. Transfusion Medicine Update, The Institute for Transfusion Medicine, Issue #5 [On-line information]. Available online at http://www.itxm.org/TMU2002/Issue5.htm through http://www.itxm.org.

Menta, S. (1999 Spring). The Coagulation Cascade. Physiology Disorders Evaluation, College of Medicine, Univ of Florida [On-line information]. Available online at http://www.medinfo.ufl.edu/year2/coag/title.html through http://www.medinfo.ufl.edu.

Elstrom, R. (2001 November 10, Updated). Factor X assay. MEDLINEplus Health Information, Medical Encyclopedia [On-line information]. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/003680.htm.

Elstrom, R. (2001 November 10, Updated). Factor II assay. MEDLINEplus Health Information, Medical Encyclopedia [On-line information]. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/003674.htm.

Elstrom, R. (2001 November 10, Updated). Factor II deficiency. MEDLINEplus Health Information, Medical Encyclopedia [On-line information]. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/000549.htm.

Elstrom, R. (2001 November 10, Updated). Factor IX assay. MEDLINEplus Health Information, Medical Encyclopedia [On-line information]. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/003679.htm.

Elstrom, R. (2001 October 6, Updated). Hemophilia B. MEDLINEplus Health Information, Medical Encyclopedia [On-line information]. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/000539.htm.

Elstrom, R. (2001 November 10, Updated). Factor V assay. MEDLINEplus Health Information, Medical Encyclopedia [On-line information]. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/003675.htm.

Elstrom, R. (2002 May 6, Updated). Factor V deficiency. MEDLINEplus Health Information, Medical Encyclopedia [On-line information]. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/000550.htm.

Elstrom, R. (2001 October 28, Updated). Platelet aggregation test. MEDLINEplus Health Information, Medical Encyclopedia [On-line information]. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/003669.htm.

Elstrom, R. (2001 November 25, Updated). Fibrinogen. MEDLINEplus Health Information, Medical Encyclopedia [On-line information]. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/003650.htm.

Elstrom, R. (2001 November 13, Updated). Antithrombin III. MEDLINEplus Health Information, Medical Encyclopedia [On-line information]. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/003661.htm.

Elstrom, R. (2001 October 28, Updated). Protein S. MEDLINEplus Health Information, Medical Encyclopedia [On-line information]. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/003660.htm.

Elstrom, R. (2001 October 9, Updated). Factor VIII assay. MEDLINEplus Health Information, Medical Encyclopedia [On-line information]. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/003678.htm.

Elstrom, R. (2001 October 14, Updated). Factor X deficiency. MEDLINEplus Health Information, Medical Encyclopedia [On-line information]. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/000553.htm.

Elstrom, R. (2001 October 14, Updated). Factor XII (Hageman factor) deficiency. MEDLINEplus Health Information, Medical Encyclopedia [On-line information]. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/000545.htm.

Elstrom, R. (2001 November 10, Updated). Factor XII assay. MEDLINEplus Health Information, Medical Encyclopedia [On-line information]. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/003681.htm.

Elstrom, R. (2001 November 25, Updated). PT. MEDLINEplus Health Information, Medical Encyclopedia [On-line information]. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/003652.htm.

Elstrom, R. (2001 October 28, Updated). Protein C. MEDLINEplus Health Information, Medical Encyclopedia [On-line information]. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/003659.htm.

Elstrom, R. (2001 November 25, Updated). PTT. MEDLINEplus Health Information, Medical Encyclopedia [On-line information]. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/003653.htm.

Elstrom, R. (2001 November 3, Updated). Fibrin degradation products. MEDLINEplus Health Information, Medical Encyclopedia [On-line information]. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/003655.htm.

Elstrom, R. (2001 October 21, Updated). Bleeding disorders. MEDLINEplus Health Information, Medical Encyclopedia [On-line information]. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/001304.htm.

Elstrom, R. (2001 November 10, Updated). Factor VII assay. MEDLINEplus Health Information, Medical Encyclopedia [On-line information]. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/003676.htm.

Elstrom, R. (2001 October 14, Updated). Factor VII deficiency. MEDLINEplus Health Information, Medical Encyclopedia [On-line information]. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/000548.htm.

Matsui, W. (2002 May 5, Updated). Primary or secondary fibrinolysis. MEDLINEplus Health Information, Medical Encyclopedia [On-line information]. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/000577.htm.

Matsui, W. (2002 February 2, Updated). Congenital antithrombin III deficiency. MEDLINEplus Health Information, Medical Encyclopedia [On-line information]. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/000558.htm.

Kovacs, B. (2001 November 26, Updated). Systemic lupus erythematosus. MEDLINEplus Health Information, Medical Encyclopedia [On-line information]. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/000435.htm.

What is a Bleeding Disorder?, History. National Hemophilia Foundation, Bleeding Disorders Info Center [On-line information]. Available online at http://www.hemophilia.org/bdi/bdi_history.htm through http://www.hemophilia.org.

What is a Bleeding Disorder? National Hemophilia Foundation, Bleeding Disorders Info Center [On-line information]. Available online at http://www.hemophilia.org/bdi/bdi_general.htm through http://www.hemophilia.org.

Hemophilia A (Factor VIII Deficiency). National Hemophilia Foundation, Bleeding Disorders Info Center [On-line information]. Available online at http://www.hemophilia.org/bdi/bdi_types1.htm through http://www.hemophilia.org.

Bauer, K. (2001). The Thrombophilias: Well-Defined Risk Factors with Uncertain Therapeutic Implications. Ann Intern Med. 2001;135:367-373 [Journal]. Available online through http://www.annals.org.

DeLoughery, T. (1999 March 15). Tests of Hemostasis and Thrombosis. OHSU [Online student handout]. Available online at http://www.ohsu.edu/som-hemonc/handouts/deloughery/printtest.html through http://www.ohsu.edu.

American Cancer Society (July 2003). Heparin a Better Choice for Cancer Patients with Clots. (Online information, accessed April 2007). Available online through http://www.cancer.org.

Bren, L, U.S. FDA Consumer Magazine (Nov-Dec 2004). Avoid Deep Vein Thrombosis: Keep the Blood Flowing. (Accessed April 2007). Available online at http://www.fda.gov/fdac/features/2004/604_vein.html through http://www.fda.gov.

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