Hypercoag Disorders

What is it?
Activation problems
Regulation problems
Breakdown problems
Other factors
Laboratory tests
Treatments
Sources

Other factors associated with an increased risk of inappropriate blood clot formation:

Venous stasis – also known as “coach-class” syndrome, this describes any situation that immobilizes someone for long periods of time, such as cramped seating during travel or prolonged bed rest with an illness or after surgery. Immobility may lead to slow or restricted blood flow (venous stasis) and an increased risk of developing a blood clot especially in the deep veins of the legs (DVT).

Elevated levels of homocysteine increase the risk of a heart attack.

Heart Failure -- may cause slowing of blood flow (stasis)

Obesity

Oral contraceptives and hormone replacement therapy

Pregnancy

Surgery -- allows the exposure of blood to tissue factor

Atrial fibrillation (rapid, uneven heartbeat) -- associated with an increase risk of stroke

Cancer – Cancers or malignancies such as leukemia may cause hypercoagulable states for a variety of reasons. 1) Tumor growth may cause external compression on a blood vessel, or, in some cases, actually extend into the vasculature (for example, renal cell cancers extending into the renal veins). 2)Treatments for cancer (radiation, chemotherapy) may leave patients more susceptible to hypercoagulation.