Why get tested?
To screen for cystic fibrosis (CF) and pancreatic insufficiency by evaluating pancreatic function

When to get tested?
When you or your infant have symptoms of pancreatic insufficiency such as persistent diarrhea, foul-smelling bulky greasy stools, malnutrition, and vitamin deficiency; these are also symptoms of cystic fibrosis (CF), so trypsinogen may be ordered as part of newborn general population screening and/or if a newborn has meconium ileus (no stools in the first 24 to 48 hours of life)

Sample required?
A blood sample drawn from an infant’s heel, a spot of blood that is put onto filter paper, or a blood sample drawn from a vein in the arm