Thyroid Antibodies

Also known as: Thyroid autoantibodies; Antithyroid antibodies; Antimicrosomal antibody; Thyroid microsomal antibody; Thyroperoxidase antibody; TPOAb; Anti-TPO; TBII; Antithyroglobulin antibody; TgAb; TSH receptor antibody; TRAb; Thyroid stimulating immunoglobulin; TSI

Formal name: Thyroid peroxidase antibody (TPOAb); Thyroglobulin antibody (TgAb); Thyroid stimulating hormone receptor antibody (TRAb)

Related tests: T3; T4; TSH; Thyroglobulin

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NOTE: This article is based on research that utilizes the sources cited here as well as the collective experience of the Lab Tests Online Editorial Review Board. This article is periodically reviewed by the Editorial Board and may be updated as a result of the review. Any new sources cited will be added to the list and distinguished from the original sources used.

Sources Used in Current Review

Wu, A. (2006). Tietz Clinical Guide to Laboratory Tests, Fourth Edition. Saunders Elsevier, St. Louis, Missouri. Pp 1030-1037.

Poppe, K. et. al. (2008 May 27). The Role of Thyroid Autoimmunity in Fertility and Pregnancy CME. Medscape from Nat Clin Pract Endocrinol Metab. [On-line information]. Available online at http://www.medscape.com/viewarticle/574861 through http://www.medscape.com. Accessed on 11/1/08.

Ogunyemi, D. and Nguyen, P. (2008 March 17). Autoimmune Thyroid Disease and Pregnancy. eMedicine [On-line information]. Available online at http://www.emedicine.com/med/TOPIC3261.HTM through http://www.emedicine.com. Accessed on 11/1/08.

Hershman, J. (2008 June, Revised). Hashimoto's Thyroiditis. Merck Manual for Healthcare Professionals [On-line information]. Available online at http://www.merck.com/mmpe/sec12/ch152/ch152d.html?qt=thyroid%20antibodies&alt=sh through http://www.merck.com. Accessed on 11/1/08.

Mayo Clinic Staff (2007 February 1). Hashimoto's disease. MayoClinic [On-line information]. Available online at http://www.mayoclinic.com/health/hashimotos-disease/DS00567 through http://www.mayoclinic.com. Accessed on 11/1/08.

Meikle, A. (2008 September). Thyroid, Autoimmune. ARUP Consult [On-line information]. Available online at http://www.arupconsult.com/Topics/EndocrineDz/ThyroidAutoimmune.html through http://www.arupconsult.com. Accessed on 11/1/08.

Sources Used in Previous Reviews

Thomas, Clayton L., Editor (1997). Taber’s Cyclopedic Medical Dictionary. F.A. Davis Company, Philadelphia, PA [18th Edition].

Pagana, Kathleen D. & Pagana, Timothy J. (2001). Mosby’s Diagnostic and Laboratory Test Reference 5th Edition: Mosby, Inc., Saint Louis, MO.

Christopher, L. (2003 August 4, Updated). Antithyroglobulin Antibody. MedlinePlus Medical Encyclopedia [On-line information]. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/003557.htm.

Christopher, L. (2003 August 2, Updated). Antithyroid microsomal antibody. MedlinePlus Medical Encyclopedia [On-line information]. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/003556.htm.

Rennert, N. (2004 April 19, Updated). Chronic thyroiditis (Hashimoto’s disease). MedlinePlus Medical Encyclopedia [On-line information]. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/000371.htm.

Thyroid Specific Autoantibodies (TPOAb, TgAb and TRAb). Thyroid Disease Manager, The Thyroid and Its Diseases, Chapter 6a, Assay of Thyroid Hormones and related Substances [On-line Book]. Available online at http://www.thyroidmanager.org/FunctionTests/assay-frame.htm through http://www.thyroidmanager.org.

Mary Ann Liebert, Inc. (2003 June 04). Thyroid Tests for the Clinical Biochemist and Physician, Thyroid Autoantibodies (TPOAb, TgAb and TRAb). Medscape from Thyroid 13(1):45-56, 2003 [On-line information]. Available online at http://www.medscape.com/viewarticle/452668?src=search through http://www.medscape.com.

Slatosky, J. et. al. (2000 February 15). Thyroiditis: Differential Diagnosis and Management. American Family Physician [On-line journal]. Available online at http://www.aafp.org/afp/20000215/1047.html through http://www.aafp.org.

(2002 September, Updated). Hashimoto's Disease: What It Is and How It's Treated. Familydoctor.org [On-line information]. Available online at http://familydoctor.org/548.xml through http://familydoctor.org.

(© 2005). Thyroglobulin and Thyroglobulin Antibody. ARUP’s Guide to Clinical Laboratory Testing [On-line information]. Available online at http://www.aruplab.com/guides/clt/tests/clt_234b.jsp#1149079 through http://www.aruplab.com.

(© 2005). Thyroid Peroxidase (TPO) Antibody. ARUP’s Guide to Clinical Laboratory Testing [On-line information]. Available online at http://www.aruplab.com/guides/clt/tests/clt_235b.jsp#1149126 through http://www.aruplab.com.

Jain, T. (2004 February 2, Updated). TSI. MedlinePlus Medical Encyclopedia [On-line information]. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/003685.htm.