HLA-B27
The Test Sample
What is being tested?
HLA-B27 is found in about 5-10% of the U.S. population. Its presence has been associated with several autoimmune disorders. The most common of these disorders is ankylosing spondylitis (AS). Approximately 90% of patients with AS are positive for HLA-B27. Other disorders that have an association with the presence of HLA-B27 include:
HLA-B27 may also be present in patients with inflammatory bowel disease and with a range of other chronic conditions. While HLA-B27 has not been established as a cause of these disorders, there is a higher prevalence of this antigen in those affected.
How is the sample collected for testing?
NOTE: If undergoing medical tests makes you or someone you care for anxious, embarrassed, or even difficult to manage, you might consider reading one or more of the following articles: Coping with Test Pain, Discomfort, and Anxiety, Tips on Blood Testing, Tips to Help Children through Their Medical Tests, and Tips to Help the Elderly through Their Medical Tests.
Another article, Follow That Sample, provides a glimpse at the collection and processing of a blood sample and throat culture.
Is any test preparation needed to ensure the quality of the sample?






