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First Trimester
Down Syndrome Screen

Article Sources

NOTE: This article is based on research that utilizes the sources cited here as well as the collective experience of the Lab Tests Online Editorial Review Board. This article is periodically reviewed by the Editorial Board and may be updated as a result of the review. Any new sources cited will be added to the list and distinguished from the original sources used.

We have included the web address to online sources used in developing and reviewing this article for documentation purposes only. Links included on this Sources page are valid, working links at the time they are posted. Please be aware that the source owner may, from time to time, reorganize the source web site, which can result in broken links on our pages. If you wish to access a source and come across a broken link, you may still be able to access it by entering just the parent web address in your browser's address bar (eg, "www.nih.gov") and then by entering the source title in the site's search feature.

S1
Pagana, Kathleen D. & Pagana, Timothy J. (© 2007). Mosby’s Diagnostic and Laboratory Test Reference 8th Edition: Mosby, Inc., Saint Louis, MO. Pp 710 – 713.

S2
Thomas, Clayton L., Editor (1997). Taber’s Cyclopedic Medical Dictionary. F.A. Davis Company, Philadelphia, PA [18th Edition].

S3
Newberger, D. (2000 August 15). Down Syndrome: Prenatal Risk Assessment and Diagnosis [23 paragraphs]. Accessed on 4/15/07. American Family Physician [On-line journal]. Available FTP: http://www.aafp.org/afp/20000815/825.html

S4
Qin, Q., et. al. (2002). Point-of-Care Time-resolved Immunofluorometric Assay for Human Pregnancy-associated Plasma Protein A: Use in First-Trimester Screening for Down Syndrome [Pages 1-3 of 20]. Accessed on 4/15/07. Clinical Chemistry 48:473-483 [On-line journal]. Available FTP: http://www.clinchem.org/cgi/content/full/48/3/473

S5
(2007 January). Maternal Blood Screening for Birth Defects [39 paragraphs]. March of Dimes [On-line information]. Accessed on: 4/15/07. Available FTP: http://www.marchofdimes.com/printableArticles/14332_1166.asp

S6
Barclay, L. and Lie, D. (2007 January 4). New Guidelines Recommend Universal Prenatal Screening for Down Syndrome [18 paragraphs]. Medscape Medical News [On-line information]. Accessed on: 4/10/07 Available FTP: http://www.medscape.com/viewarticle/550256_print

S7
Cleary-Goldman, J. and Malone, F. (2005 September 26). Advances in Prenatal Diagnosis [42 paragraphs]. Medscape from Appl Radiol 2005;34(9):8-18 [On-line information]. Accessed on: 4/10/07 Available FTP: http://www.medscape.com/viewarticle/513126_print

S8
Cole, D.S. (© 2005). Advances in First-Trimester Prenatal Diagnosis: Combined, Integrated, or Amniocentesis? [10 paragraphs] Medscape Conference Coverage: American College of Obstetricians and Gynecologists 53rd Annual Clinical Meeting [On-line information]. Accessed on: 4/10/07 Available FTP: http://www.medscape.com/viewprogram/4078_pnt

S9
American College of Radiology and the Radiological Society of North America. Radiology Info, Obstetric ultrasound (online information, accessed June 2007). Available FTP: http://www.radiologyinfo.org/en/info.cfm?PG=obstetricus

S10
Malone FD, et al. First Trimester or Second Trimester Screening or Both for Down Syndrome. New England Journal of Medicine. 2005;353:2001–2011.

S11
ACOG News Release (January 2, 2007). New Recommendations for Down Syndrome Call for Screening of All Pregnant Women. On the Internet: http://www.acog.org/from_home/publications/press_releases/nr01-02-07-1.cfm

S12
ACOG Practice Bulletin Clinical Management Guidelines for Obstetrician-Gynecologists. Number 77, January 2007. Screening for Fetal Chromosomal Abnormalities. Obstetrics & Gynecology 2007; 109:217-227.



This article was last reviewed on July 5, 2007.


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