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Diabetes-related Autoantibodies
Also known as: Islet autoantibodies Formal name: Islet Cell Cytoplasmic Autoantibodies (ICA), Insulin Autoantibodies (IAA), Glutamic Acid Decarboxylase Autoantibodies (GADA, GAD65 Autoantibodies), Insulinoma-Associated-2 Autoantibodies (IA-2A), ICA512 Autoantibodies, Protein Tyrosine Phosphatase-like Autoantibodies Related tests: Glucose, Insulin
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Common Questions
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1. Do ICA, GADA, and IA-2A destroy the beta cells?
2. Does early detection of beta call destruction allow its prevention?
1. Do ICA, GADA, and IA-2A destroy the beta cells?
They are associated with beta cell destruction and reflect an ongoing autoimmune process, but they are not thought to cause the damage.
2. Does early detection of beta call destruction allow its prevention?
Not currently. What it does do is allow for diabetes to be addressed as soon as symptoms such as frequent urination, weight loss, and hyperglycemia appear. This can help establish diabetic glucose control and can in turn help minimize the occurrence of complications such as the kidney and eye damage that are seen with diabetes.
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This article was last reviewed on
January 30, 2006.
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