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CD4 Count

Also known as: T4 count, T-helper cells
Related tests: HIV viral load
The Test Sample
 
What is being tested?
This test measures the number of CD4 cells (also known as T-helper cells) in your blood and assesses the status of your immune system. CD4 cells are a type of white blood cell that fight infection, and they play an important role in your immune system. They help to identify, attack, and destroy specific bacteria, fungi, and other germs that affect the body. CD4 cells are made in the spleen, lymph nodes, and thymus gland, and they circulate throughout the body in the bloodstream. CD4 cells are a major target for HIV, which binds to the surface of CD4 cells, enters them, and either reproduces immediately, killing them in the process, or remains in a resting state, reproducing later. As the HIV virus gets into the cell and replicates, the number of CD4 cells in the blood gradually declines. As HIV disease progresses, the CD4 count will go down and as treatment reduces the progression, the CD4 count will go back up.

How is the sample collected for testing?
Blood is drawn by needle from a vein in your arm.

NOTE: If undergoing medical tests makes you or someone you care for anxious, embarrassed, or even difficult to manage, you might consider reading one or more of the following articles: Coping with Test Pain, Discomfort, and Anxiety, Tips on Blood Testing, Tips to Help Children through Their Medical Tests, and Tips to Help the Elderly through Their Medical Tests.

Another article, Follow That Sample, provides a glimpse at the collection and processing of a blood sample and throat culture.





This article was last reviewed on March 7, 2005.
 
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