1. Is CA-125 always increased in ovarian cancer?
No, not all ovarian cancers are associated with increased levels of CA-125. Elevated levels have been found in about 80% of women with ovarian cancer.
2. My CA-125 is elevated. Does that mean I have cancer?
No. CA-125 may be elevated in several other conditions and diseases. This means it is not specific for ovarian cancer. CA-125 may normally be increased in early pregnancy and during menstruation. It can also be increased in diseases such as pelvic inflammatory disease or endometriosis and sometimes in hepatitis and cirrhosis of the liver.
3. Does ovarian cancer run in families?
Family history is a risk factor for ovarian cancer. If you have close family members who have had ovarian cancer, you are at higher risk than someone who has no family history of the disease. Make sure your doctor knows about your family medical history.
