|
|
|
|
|
|
BRCA-1 and BRCA-2
Also known as: BRACA
Formal name: Breast Cancer Gene 1 and Breast Cancer Gene 2
|
|
|
|
      |
|
|
Common Questions
|
| |
1. If the BRCA test is positive, what are my options?
2. If the BRCA test is negative, how likely/unlikely am I to get breast or ovarian cancer?
3. Where can I get this test?
1. If the BRCA test is positive, what are my options?
If the BRCA test is positive, the options include increased frequency of check-ups (e.g., mammography, blood tests for CA-125, or transvaginal ultrasonography); medications that could reduce risk (e.g., oral contraceptives or tamoxifen); or surgical removal of the ovaries or breasts. There are a number of variables involved and it is important to discuss your options with your doctor and genetic counselor.
2. If the BRCA test is negative, how likely/unlikely am I to get breast or ovarian cancer?
Research studies have reported that for every 1000 women negative for BRCA mutations, between 12 and 45 of them will develop breast cancer by age 50 and between 3 and 4 will develop ovarian cancer by age 50. The risk increases with age.
3. Where can I get this test?
The test can be ordered by a doctor, preferably by one who can also offer genetic counseling. The blood sample will be sent to a laboratory that specializes in BRCA testing. The American Society of Clinical Oncology and the National Breast Cancer Coalition encourage women seeking the test to participate in long-term outcome studies to help gather information on the effectiveness of different check-up and treatment options.
|
|
|
This article was last reviewed on
November 23, 2005.
|
| |
|
|
|
|
|
|
|
